Research Highlights

  • Genomics
  • Drug Discovery
  • Databases

  • Structural Bioinformatics
  • Computational Biology
  • Database Development
  • Proteomics
  • Drug Designing
Completed Minor Projects
  1. Modeling and inhibition of airborne fungal allergen proteins using In silico Biology
  2. Comparative Evolutionary analysis of Fungi found in Lampito mauritii burrow wall
  3. Phylogenetic Analysis of the Fungi isolated from Lampito mauritii burrow wall with references to enzymes Amylase and cellulase
  4. In silico Analysis of potent bioactive compound targeting fungal pathogenic proteins
  5. Database on antifungal plant compounds
  6. Identification of structural patterns in airborne Allergic Fungal Proteins.
  7. In silico Structure prediction and characterization of allergic Fungal Proteins
  8. Promoter prediction and Genome Comparision of six strains of Salmonella enterica
  9. Virtual Screening for identification of anti-fungal lead plant compound against Metalloproteinase of Aspergillus fumigatus.

  10. Phylogenetic analysis on the Metalloprotienase of Aspergillus Fumigatus woth various fungal species - An in silico study.
  11. Exploring th antagonist property of Allicin against Cysteine proteinase from Entamokeba histolytica
  12. Identification of Potent Inhibitor for RNA Dependent RNA polymerase (RDRP) of Dengue Virus Serotype-3: A Molecular Docking Study.
  13. RDIS: The Rabies Diesase Information System
Completed Major Projects
  • Database on Indian Earthworms
  • Database on Airborne Fungal Allergens

Research Papers Published during 2015-16

  1. Sankarasubramanian J, Pavithra KB, Kavitha B (2015) Identification of Potent Inhibitor for RNA Dependent RNA polymerase (RDRP) of Dengue Virus Serotype-3: A Molecular Docking Study. J Appl Bioinform Comput Biol 4:1. 
  2. Babu Gowda, Mallappa M., Jayant I. Gowda, Raghavendran Rengasamy. Interaction of Ketoconazole with Bovine Serum Albumin: Electrochemical, Spectroscopic and Molecular Modeling Studies. J App Pharm Sci, 2015; 5 (Suppl 2): 037-044. 
  3. Dharmalingam & Lydia, RDIS: Rabies Disease Information System. Bioinformation 11(11): 506-508 (2015) 
  4. P. Ethalsha, Dr. Lydia J, Dr. A. Malar Retna. Docking studies of the isolated compound from C. roseus: 19-hydroxy lochnericine - with various breast cancer drug targets. Accepted in GIAP Journals.
  5. Lydia J, Sudarsanam D, Anticarcinogenic effects of selected alkaloids isolated from Cyperus rotundus: An insilico perspective. Accepted in J Appl Bioinform Comput Bio.
  6. Pavan R. Gowda, Ravishankar, V. Rai, Asma Saqib, Lydia J, Marula Siddha Swamy, Chandrakant S. Karigar and Shailasree S. High throughput  screening  by  in  silico  molecular  docking  of Eryngium  foetidum (Linn.) bioactives for Cylcooxygenase 2 inhibition

Research Papers Presented in the 8th National Women's Science Congress, held at the UAS campus, Hebbal, Bangalore on the 7th and 8th of November 2015

  1. Functional annotation of selected proteins from the chromosome 1 of Neurospora crassa By Anjali M  and Lydia J.
  2. Phylogenetic Analysis and Restriction Digestion Of Ctx-M-15 Bacterial Strains By Kushnuda Tarannum, Arun Jyothi Mathias, Lydia J.
  3. Docking study of Carbapenam resistant KPC-2 carbapenemase of Klebsiella pneumonia with Apigenin isolated from Holy Basil By Vidhya N, Arun Jyothi Mathias, Lydia J. This presentation Won The Young Scientist Award.

Research Papers Presented in the 9th National Women's Science Congress, held at Doddabalapura, Bangalore on the 7th and 8th of November 2016

  1. Kavitha B., Koushalaya G. Bhat, Ananya N. G., Swetha K. A. and Lydia J. Phylogenetic analysis of Amylase producing bacteria isolated from the casts of Pontoscolex erythrus

Posters presented at the Bangalore India Bio Conference held at Lalit Ashok, Bangalore, from the 9th to 11th of  February, 2016

  1. Putative drug isolated from C. rotundus for carbapenum resistant Klebsiella pneumoniae (NDM) By Vidhya N., Arun Jyothi Mathias, Lydia J.
  2. Synergistic effect of antibiotics on Staphyllococcus aureus: An in slilco and in vivo validation By Kunshnuda Tarannum, Visvanath t and Lydia J.
  3. Phylogenetic analysis of 21 isolates producing New Delhi Metallo-beta-lactamase Type Carbapenamase by Prathiba G, Arun Jyothi Mathias and Lydia J.

Research Papers Communicated

  • Lydia J,Pharmacodynamic and Pharmacokinetic Features of 100 Medicinally Significant Plant Phenols.
  • Ethalsha P., Malar Ratna T. and Lydia J, In vitro and in silico anticarcinogenic interactions of Horhamerricine isolated from Catharanthus roseus compared to Tamoxifen.
  • Arun Jyothi Mathias, Pavithra K B, Lydia J,  Structure prediction, evaluation and IgE interaction of 10 allergenic proteins of Alternaria alternate.
  • In silico studies on the anticarcinogenic and anti diabetic effects of putative compounds from S. cuminis seed extracts.